Dr.Ceuracle PDRN & Retinol Shot Ampoule is an intensive skincare ampoule that combines two of the most recognized ingredients in modern Korean skincare – PDRN and retinol – in a formula designed for skin that needs more advanced care for elasticity, fine lines, and uneven skin texture.
The formula contains Sodium DNA (PDRN) along with Salmon Egg Extract and retinol. This combination is developed to care for skin that feels less supple and helps to provide a firmer, smoother, and more vital skin appearance.
A particularly interesting part of the formula is Hydrolyzed Sponge, also known as spicules. These microscopic structures are used in some advanced skincare products and can give a characteristic slight stinging sensation upon application. They contribute to the product's intensive "shot" concept and distinguish the ampoule from traditional retinol serums.
To balance the active formula, the ampoule also contains Ceramide NP, Centella Asiatica, beta-glucan, squalane, and Hydrolyzed Sodium Hyaluronate, which help to hydrate, soothe, and care for the skin barrier.
The result is a multifunctional ampoule for those who want to focus on fine lines, elasticity, firmness, skin texture, and a more even skin appearance in one product.
PDRN + Retinol + Spicules
PDRN – Sodium DNA
The formula contains Sodium DNA, the INCI designation used for PDRN-related ingredients in skincare.
PDRN is primarily used in products developed for skin that needs care for:
Decreased elasticity
Uneven skin texture
Fine lines
Tired and dull skin
Skin that needs a more vital appearance
Retinol
Retinol is a form of vitamin A and one of the most well-documented cosmetic ingredients for skin structure and visible signs of aging.
With regular use, retinol helps to:
Improve skin texture
Reduce the appearance of fine lines
Give a smoother skin appearance
Improve the feeling of firmness
Contribute to a more even skin tone
Spicules – Hydrolyzed Sponge
Hydrolyzed Sponge consists of microscopic structures, often called spicules, used in some intensive skincare formulations.
The product may therefore cause a slight stinging or tingling sensation during or after application. This differs from the texture of a traditional serum or a regular ampoule.
Properties
Firmness & elasticity
The combination of PDRN and retinol is designed for skin that feels less elastic and helps to provide a smoother and firmer skin appearance.
Care for fine lines
Retinol supports the skin's natural renewal process and, with regular use, helps to reduce the appearance of fine lines and uneven skin texture.
Refined skin texture
The formula targets skin that feels uneven or rough and helps to provide a smoother and more refined skin appearance.
Barrier-caring ingredients
Ceramide NP, Hydrogenated Lecithin, and squalane complement the active ingredients and help to care for the skin's natural barrier.
Hydration
Glycerin, Hydrolyzed Sodium Hyaluronate, and beta-glucan help to bind moisture and prevent the skin from feeling dry.
Soothing care
Centella Asiatica and beta-glucan complement the intensive formula with soothing and caring properties.
Key ingredients
PDRN / Sodium DNA
One of the product's main profiling ingredients. PDRN is used in skincare with a focus on a firmer, more even, and more vital skin appearance.
Retinol
Vitamin A derivative that helps to improve skin texture, fine lines, and visible signs of aging with regular use.
Hydrolyzed Sponge
Microscopic spicules that give the product its characteristic "shot" concept and can create a slight stinging sensation upon application.
Salmon Egg Extract
Salmon roe extract that complements the product's PDRN-inspired formula.
Ceramide NP
A skin-identical lipid that helps to support the skin's natural barrier and maintain moisture.
Centella Asiatica
The formula contains both Centella Asiatica Extract and Centella Asiatica Leaf Extract, well-known caring ingredients that help to soothe the skin.
Beta-Glucan
A hydrating and soothing ingredient that helps to support the skin's moisture balance.
Squalane
Emollient ingredient that helps to reduce the feeling of dryness and care for the skin barrier.
Hydrolyzed Sodium Hyaluronate
A form of hyaluronic acid that helps the skin bind moisture and provides a softer, more hydrated feel.
Recommended for:
Normal skin
Dry skin
Combination skin
Mature skin
Skin with fine lines
Decreased elasticity
Skin that feels less firm
Uneven skin texture
Dull skin
Those who want to start addressing visible signs of aging
Those looking for PDRN in their skincare routine
Those who want to combine PDRN and retinol
Those who are accustomed to active skincare products
For very sensitive or reactive skin, I would not position it as a first choice, primarily due to the combination of retinol and Hydrolyzed Sponge.
Consistency
A concentrated, light ampoule that spreads over the skin and absorbs before subsequent skincare steps.
Due to Hydrolyzed Sponge/spicules, the skin may experience a slight tingling or stinging sensation during or after application.
HOW TO USE
Apply a small amount of Dr.Ceuracle PDRN & Retinol Shot Ampoule to cleansed skin and gently pat the product until absorbed.
Since the formula contains retinol and spicules, I recommend introducing the product gradually.
For example, start with 2–3 evenings a week and gradually increase the frequency of use depending on your skin's tolerance.
Follow with a moisturizing face cream.
Always use sunscreen during the day.
Good to know
Can the product sting on the skin?
Since the formula contains Hydrolyzed Sponge/spicules, a slight stinging or tingling sensation may occur upon application.
If you experience severe or persistent irritation, discontinue use.
Can it be combined with other active ingredients?
Since the ampoule already contains retinol and spicules, I would avoid introducing several powerful active products simultaneously.
Be especially careful when using it in the same routine as strong AHA/BHA exfoliants, other retinoids, or other intensive spicule products.
Safety information:
For external use only. Avoid the area directly around the eyes and lips, as well as broken or severely irritated skin.
Introduce the product gradually and adjust use according to your skin's tolerance.
Discontinue use if severe or persistent irritation occurs.
Use high SPF sunscreen during the day when using retinol.
If pregnant or breastfeeding, it is recommended to consult a doctor or midwife before using products containing retinoids.
Store in a cool, dry place, protected from direct sunlight and out of reach of children.
INGREDIENTS
Water, Glycerin, Dipropylene Glycol, Isododecane, 1,2-Hexanediol, Glycereth-26, C12-15 Alkyl Benzoate, Polyglyceryl-3 Distearate, Butylene Glycol, Diethoxyethyl Succinate, Squalane, Isopropyl Myristate, Coptis Japonica Root Extract, Glyceryl Stearate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Ammonium Acryloyldimethyltaurate/VP Copolymer, Dioscorea Japonica Root Extract, Hydrogenated Lecithin, Ethylhexylglycerin, Tromethamine, Glyceryl Stearate Citrate, Xanthan Gum, Hydrolyzed Sponge, Hydrolyzed Corn Starch, Beta-Glucan, Disodium EDTA, Sucrose, Dextrin, Cyanocobalamin, Theobroma Cacao (Cocoa) Seed Extract, Hydrolyzed Sodium Hyaluronate, Centella Asiatica Extract, Ficus Carica (Fig) Fruit Extract, Lactococcus Ferment Lysate, Ceramide NP, Fructooligosaccharides, Sodium DNA, Cyperus Rotundus Root Extract, Salmon Egg Extract, Centella Asiatica Leaf Extract, Sodium Chloride, Retinol, Citric Acid.
Please note:
Ingredient lists may be updated in conjunction with product improvements or changes from the manufacturer. We therefore recommend that you always check the current ingredient list on the product packaging or on the brand's official website for the most up-to-date information.
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